Platinum ototoxicity
WebbPlatinum ototoxicity was also attributed to free radical-induced cell damage, and antioxidant as well as platinum detoxifying mechanisms may protect from its … WebbWe studied 78 pediatric patients (155 ears) with localized brain tumors treated in 1997–2001 who had not received platinum-based chemotherapy and were followed up for at least 48 months. They were evaluated prospectively by means of serial pure-tone audiograms (250 Hz–8 kHz) and/or auditory brainstem response before and every 6 …
Platinum ototoxicity
Did you know?
WebbUS20240087073A1 US17/957,476 US202417957476A US2024087073A1 US 20240087073 A1 US20240087073 A1 US 20240087073A1 US 202417957476 A US202417957476 A US 202417957476A US 2024087073 A1 US2024087073 A1 US 2024087073A1 Authority US United States Prior art keywords cancer complex pharmaceutically acceptable formula … WebbPlatinum-based therapy is the mainstay for management of high-risk neuroblastoma. Prevalence of platinum-related ototoxicity has ranged from 13% to 95% in previous …
WebbPlatinum-based therapy is the mainstay for management of high-risk neuroblastoma. Prevalence of platinum-related ototoxicity has ranged from 13% to 95% in previous reports; variability is attributable to small samples and disparate grading scales. There is no consensus regarding optimal ototoxicity grading. WebbCisplatin, carboplatin, nedaplatin, and oxaliplatin are widely used in contemporary oncology; however, their ototoxic and neurotoxic side effects are quite different as …
WebbAntineoplastic lecture notes antineoplastic agents antineoplastics alkylating agents and platinum compounds common examples: alkylating agents chlorambucil (Skip to document. Ask an Expert. Sign in Register. Sign in Register. Home. Ask an Expert New. My Library. Discovery. WebbStudy of different transporters involved in the uptake of platinum compounds and taxanes. These uptakes induce known side effects as neurotoxicity, ototoxicity and nephrotoxicity.
Webb20 aug. 2024 · Platinum nanoparticles have also been used in the diagnosis of diseases [ 16, 17, 18 ]. Therefore, this review focuses on recent reports on the functionalization of platinum nanoparticles with bioactive molecules such as antibodies, biocompatible polymers, peptides, and biomolecules, among others, and their biomedical applications. 2.
WebbPrescription drug information for thousands of brand, generic, and OTC medicines is available to registered members only. It's FREE to register and you'll have access to drug information and much more. gas log fireplace inserts with blowerWebb~ First Therapy Recommended for Approval in the European Union for Reducing the Risk of Cisplatin-induced Hearing Loss (Ototoxicity) in Pediatric Patients with Localized, Non-metastatic Solid Tumors~ david cross make america great againWebbTitle: Cisâ platinum Ototoxicity: Clinical experience and temporal bone histopathology: Created Date: 10/9/2006 5:15:09 PM gas log fireplaces australiaWebb8 okt. 2012 · Nedaplatin, a second generation platinum drug, is used to treat many of the same types of cancers as cisplatin. Nedaplatin is considered less nephrotoxic and … david cross md richmond vaWebbDeterminants of ototoxicity in 451 platinum-treated Dutch survivors of childhood cancer : A DCOG late-effects study: Published in: European Journal of Cancer, 69, 77 - 85. ... Cisplatin, Carboplatin, Ototoxicity, Childhood cancer, Munster classification, Furosemide, PEDIATRIC ONCOLOGY PATIENTS, PRACTICAL GRADING SYSTEM, INDUCED HEARING … gaslog fireplace repair hiltonheadWebb20 dec. 2024 · Unfortunately, platinum-based therapies cause ototoxicity in many patients, and are particularly harmful to the survivors of pediatric cancer. Each year in the U.S. and … david cross moviesWebb24 juli 2024 · Platinum chemotherapeutics and other free-radical inducing therapies, such as radiotherapy, can cause multiple systemic and neurological side effects. In children, … gas log fireplaces vented