Phospho-sting-s365
WebMay 22, 2024 · Macrophage-stimulator of interferon genes (STING) signaling mediated sterile inflammation has been implicated in various age-related diseases. However, whether and how macrophage mitochondrial DNA (mtDNA) regulates STING signaling in aged macrophages remains largely unknown. WebWestern blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for …
Phospho-sting-s365
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WebMouse Phospho-STING (Ser365) control lysateHTRF® This lysate is a component of the Mouse Phospho-STING (Ser365) kit. It may be used as a residue specific positive control … WebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). Spécificité
WebJul 7, 2024 · To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary conserved... WebAnti-STING Antibody from Assay Genie is a high quality, highly sensitive antibody with reactivity against Human, Mouse, Rat and validated in WB IHC. ... Phospho-STING-S365 Rabbit pAbProduct Code:CABP1199Size:20uL, 50uL, 100uLSynonyms:ERIS, MPYS, Mita, STING, Tmem173, CABP1199
WebPhospho-STING (Ser365) (D8W4F) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser365. Species … WebMouse Phospho-STING (Ser365) one-plate assay protocol Detection of Mouse Phosphorylated STING (Ser365) with HTRF reagents can be performed in a single plate …
WebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). 特異性
WebHTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry. sharda chemical usaWebA synthetic phosphorylated peptide around S365 of mouse STING. Post Translational Modifications. Phosphorylation by TBK1 leads to activation and production of IFN-beta. … pool cue shaper scufferWebWhole cell lysates were analyzed by WB for phospho-STING (p-STING S365), STING, phospho-TBK1 (p-TBK1 S172), TBK1, phospho-IRF3 (p-IRF3 S396), IRF3, IFIT1, cGAS and FLAG (for disA expression). β-actin levels were used as loading control. Data are representative of three independent experiments. sharda classes appWebJan 13, 2024 · We apply CARVE to rapidly generate a novel immunogenic vaccinia virus vector, which expresses a bacterial diadenylate cyclase. This novel vector, STINGPOX, produces cyclic di-AMP, a STING... pool cue shipping boxWebAntibodies against p-STING (S365), p-IRF3 (S396), p-IκBα (S32), p-TBK1 (S172), p-STAT1 (Y701), p-NF-κB p65 (S536), p-IKKε (S172), LC3A/B, and GAPDH were from Cell Signaling; … pool cues for sale near me mcdermottWebRabbit Phospho-STING-S365 Rabbit pAb (AP1199), validaed in WB and tested in Human,, Mouse. 100% Guaranteed. ABclonal provides trial size antibody samples for target … pool cues perth waWebJun 25, 2024 · In infected cells, STING is phosphorylated on S366 (S365 in mouse) and is K63 linked ubiquitinated, confirming the presence of its activated form at later time points following RNA virus infection, similarly to what has been observed by others after infection with DNA virus ( Chiang and Gack, 2024 ). Results sharda chit fund